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Now, research led by a Johns Hopkins University biologist sheds light on the subject, potentially pointing the way to a better understanding of how the structure of nerve cells in the adult hippocampus may deteriorate, which can lead to Alzheimer's disease and other neurological disorders. "It's literally a black box," said Rejji Kuruvilla, an associate professor in the Department of Biology who led the research team, referring to the biochemical signaling systems that support the neurons in the adult brain. "To get a handle on repairing the adult brain, you first need to know what those signals are." In a paper in the journal  Proceedings of the National Academy of Sciences , Kuruvilla and eight other scientists from two research institutions report that a protein that has primarily been studied for its role in early animal development also plays a surprising role in maintaining the structure of hippocampal neurons in adult mice. Chih-Ming Chen, a...

Now, a new drug that could treat Alzheimer' s disease , SAK3, has been developed by a Japanese research group led by Tohoku University Professor Kohji Fukunaga. In their study, the researchers found that the T-type calcium channel enhancer, SAK3, stimulates the release of acetylcholine in the brain and improves cognition by activating the memory molecule CaMKII. According to Professor Fukunaga, SAK3 also reduces the production of amyloid beta protein in the study's model mice. This, he says, could lead to the development of the first disease-modifying drug to prevent mild to severe Alzheimer disease. SAK3 is now in the preclinical stage of drug development, and has so far proven to be safe and well-tolerated in animal experiments. Clinical trials are expected to begin in the next few years. for more information visit our product website: Buy Kamagra Polo Online